差分

#≧4 doses/week - anal sex

*1 tablet/day

*effective for anal sex 1 day after of commencement

*effective for vaginal sex 7 days after of commencement

*2 tabltes at 2-24 hours before anal sex + 1 tablet 24-48 hours after the sex

*not effective against vaginal sex

*have to continue for a certain duration after the last sex

*

*

*test renal function every 3 mo

**annually for eGFR>90 or <40y/o

*offer STIs screening

*Renal dysfunction; eGFR<60

*Osteoprorosis

*event-based dosing is option for contraindicated people

*PROUD study

**86% reduction of HIV

*IMPACT study

==Clinical staging==