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*Diarrhea > 1 month, unexplained
*Pulmonary TB, pluribacillary
*CNS toxoplamosis (Toxoplasmoma)
*HIV encephalopathy
*CNS cryptococcal infection (Cryptococcoma)
*Progressive multifocal leukoencephalopathy
→WHO Clinical staging
==WHO Clinical staging==
{|class="wikitable" style="vertical-align:top"
|-
!style="width:4%"|Stage
!style="width:24%"|3
!style="width:24%"|4
|-style="vertical-align:top"
!Skin
|
*Herpes simplex infection (oral, genital) > 1 month
*[[Talaromycosis|Talaromycosis]] (Asia only)
|-style="vertical-align:top"
!Oral<br>GI tract
|
*Oral ulcer, recurrent
|
*'''Oral Candidiasis'''
*Oral hairy leukoplakia (EBV-associated)
*Acute necrotizing ulcerative stomatitis/gingivitis/periodontitis
*Diarrhea > 1 month, unexplained
|
*'''Esophageal Candidiasis'''
*Cryptosporidiasis, chronic
*Isosporiasis, chronic
|-style="vertical-align:top"
!Respiratory
|
*URIs, recurrent
|
*Bacterial LRIs
*Pulmonary TB, '''pluribacillary'''
|
*Severe bacterial LRIs, recurrent*Pulmonary TB, '''paucibacillary'''
*Pneumocystis pneumonia (PcP)
|- style="vertical-align:top"!Neurological||||*CNS toxoplamosis (Toxoplasmoma)*HIV encephalopathy*Severe bacterial LRIs, recurrentCNS cryptococcal infection (Cryptococcoma)*Progressive multifocal leukoencephalopathy|-style="vertical-align:top"
!Systemic
|
*Lymphadenopathy, persistent
|
*Weight loss '''<10%''', unexplained
|
*Weight loss '''>10%''', unexplained
*Fever > 1 month, unexplained
*Sever bacterial infections (LRI, bone/joint infections, meningitis)
|
*HIV wasting syndrome
*Extrapulmonary TB, extrapulmonary
*Cytomegalovirus infection
*Non-typhoidal salmonellosis (NTS), recurrent
*[[Coccidioidomycosis|coccidioidomycosisCoccidioidomycosis]] (America only)*[[Histoplasmosis|histoplasmosisHistoplasmosis]]
*Atypical disseminated leishmaniasis
*HIV-associated nephrophathy
*HIV-associated cardiomyopathy
|-style="vertical-align:top"
!Malignancy
|
