*many patients are asymptomatic and cured spontaneously
**cell-mediated immunity
**mass treatment of asymptomatic patients is very problematic because of lacking of easily taken oral short course drug
*50,000-90,000 new cases reported per year 2004-2008
*202,200-389,100 new cases estimated per year 2004-2008 - underreporting
**no good evidence
**miltefosine for 12 weeks
===cutaneous leishmania===