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ページの作成:「==epidemiology== *70-500 mil. infections per year *2.1 mil. severe dengue per year *21,000 deaths per year *significant impact on both health systems and individuals **no…」
==epidemiology==
*70-500 mil. infections per year
*2.1 mil. severe dengue per year
*21,000 deaths per year
*significant impact on both health systems and individuals
**no reliable way to predict who truely needs hospitalization
==clinical course==
===severe dengue===
*definition WHO
**warning sign
***abd pain/tenderness
***persitent vomiting
***clinical fluid accumulation
***mucosal bleeding
***lethargy
***
***
***
**severe dengue
***severe plasma leakage leading to:
***severe bleeding
***severe organ involvement
*dehydration - shock/bleeding - reasbsorption/fluid overload
*secondary organ impairment may be idiosyncratic
*risk factors of severe dengue
**young age
**female gender
**previous flavivurs/dengue infection
**genotype of dengue virus
**co-morbidity
*70-500 mil. infections per year
*2.1 mil. severe dengue per year
*21,000 deaths per year
*significant impact on both health systems and individuals
**no reliable way to predict who truely needs hospitalization
==clinical course==
===severe dengue===
*definition WHO
**warning sign
***abd pain/tenderness
***persitent vomiting
***clinical fluid accumulation
***mucosal bleeding
***lethargy
***
***
***
**severe dengue
***severe plasma leakage leading to:
***severe bleeding
***severe organ involvement
*dehydration - shock/bleeding - reasbsorption/fluid overload
*secondary organ impairment may be idiosyncratic
*risk factors of severe dengue
**young age
**female gender
**previous flavivurs/dengue infection
**genotype of dengue virus
**co-morbidity
