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==''Entamoeba histolytica''==
===epidemiology===
*some encyst in large intestine
*cysts are excreted from anus
===clinical manifestation===
*incubation a few days to years
*80% of infection are asymptomatic
*mild, extensive, extreme
*large intestine ulcer
**flask-shaped ulcer in histpathology
*advanced disease mimics ulcerative colitis and Crohn's disease
====amoebic liver abscess (ALA)====
*right lobe: left lobe =4:1
*male: female=10:1
*all age groups
**most common in 20-40 y/o
*>50% of patients have no previous dysentery
===morphology===
*trophozoite 20-50 μm
*cyst has 4 nuclei, each nucleus has a nucleolus
===treatment===
*metronidazole for trophozoite
*paromomycin for cyst eradication
==''Entamoeba dispar''==
**3:1 in developing countries
**10:1 in developed countries
==''Entamoeba coli''==
*6 nuclei in cyst
