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835 バイト追加 、 2021年4月27日 (火) 11:21
ページの作成:「==''Cryptosporidium'' spp.== *especially ''C. paravum'', ''C. hominis'' ===epidemiology=== *worldwide *2nd important pathogen for moderate-severe diarrhea before 1 year…」
==''Cryptosporidium'' spp.==
*especially ''C. paravum'', ''C. hominis''

===epidemiology===
*worldwide
*2nd important pathogen for moderate-severe diarrhea before 1 year of life

===life cycle===
*calf is reservoir of ''C. hominis''
*resistant to chlorinated water
*auto-infection in host intestine
*survive >1 year in 4-6℃ cold water
*vulnerable to dry environment
*human excretes 100 mil. cysts per day
*calf excretes 10 bil. cysts per day

===morphology===
*oocyst contains 4 sporozoites

===clinical features===
*incubation 1-12 days
*symptoms 1-2 weeks
*watery diarrhea
*abd cramps
*bloating
*fever, malaise
*weight loss
*often self-limiting
*problemable in children in developing countries, immunocompromised

===diagnosis===
*fecal microscopy
**Ziehl-Neelsen stain
**Auramine stain

===treatment===
*nitazoxianide
*paromomycin

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