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ページの作成:「==epidemiology== *1.2 mil. (~10%) of 10 mil. new cases/year are under 15 y/o in 2019 *third cause of deaths of children by infectious diseases ==special issues in childr…」
==epidemiology==
*1.2 mil. (~10%) of 10 mil. new cases/year are under 15 y/o in 2019
*third cause of deaths of children by infectious diseases
==special issues in children TB==
*children TB means recent transmission
*direct consequence of adult TB
*difficulty of diagonsis
**non-specific symptoms
**difficulty to produce sputum
**more likely to have paucibacillary lesions
***means often negative sputum smear
==risk factors==
*close contact with TB case
*HIV co-infection
*severe malnutrition
*low socioeconomic level
*promiscuity
*enclosed space
*low education for parents/care givers
==clinical features==
===latent TB===
*80-90% of children cases
*no symptoms
*Mantaux test
**IGRA is often unavailable in LMIC
*1.2 mil. (~10%) of 10 mil. new cases/year are under 15 y/o in 2019
*third cause of deaths of children by infectious diseases
==special issues in children TB==
*children TB means recent transmission
*direct consequence of adult TB
*difficulty of diagonsis
**non-specific symptoms
**difficulty to produce sputum
**more likely to have paucibacillary lesions
***means often negative sputum smear
==risk factors==
*close contact with TB case
*HIV co-infection
*severe malnutrition
*low socioeconomic level
*promiscuity
*enclosed space
*low education for parents/care givers
==clinical features==
===latent TB===
*80-90% of children cases
*no symptoms
*Mantaux test
**IGRA is often unavailable in LMIC
