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→Buruli ulcer
*transmission route unknown
**patients are often in proximity of stagnant water body
**reservoir - snails, fish, water insects, aquatic plants, koala & opposum in Australia
*undermined wound edges, thick necrotic tissue, pain is liminited
*3 months course
#edema - develops pain
#ulcer
*diagnosis - Ziehl-Neelsen stain and culture of ulcer base
*DDx - panniculitis, pyoderma gangreosum
*lipid toxin produced and secreted by ''M. ulcerans'' is pathogenetic
**highly hydrophobic
