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==Correlates of Protection==
{|class="wikitable
===Be careful===
*'''"Immune reseponses"''' contain various kinds of immunological functions, thus a single immune biomarker cannot necessarily be a CoP
**Serum antibodies with multiple isotypes and multiple functions
**Mucosal antibodies with multiple isotypes and multiple functions
**Killer T cells
**Regulatory T cells
**Natural killer cells
**Phagocytes and antigen-presenting cells
**etc.
*'''Protection against infection''' is generally different from '''protection against disease'''
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*'''Simple Single definitive cut-off of CoP is rarely not commonly available''' and '''CoP is generally relative'''
**Generally speaking, the higher a CoP biomarker is, the more highly the subject is protected from infection or disease
**In other words, a certain proportion of subjects with a certain level of CoP biomarker can be protected from infection/disease
***The proportion of protected subjects increases as the level of CoP biomarker rises
