2,994
回編集
差分
ナビゲーションに移動
検索に移動
|-*CNS toxoplamosis (Toxoplasmoma)!Malignancy*HIV encephalopathy|*CNS cryptococcal infection (Cryptococcoma)||||} {|class="wikitable"*Progressive multifocal leukoencephalopathy|-!style="width:5%"|Stage!style="width:19%"|Skin!style="widthvertical-align:19%top"|Oral & GI tract!style="width:19%"|Respiratory!style="width:19%"|Systemic!style="width:19%"|Malignancy|-!1||
|-!2*Weight loss '''<10%''', unexplained
*Herpes zoster*Papular pruritic eruptions*Seborrheic dermatitis*Fungal nail infections|*Angular cheilitis*Oral ulcer, recurrent|*URIs, recurrent|*Weight loss <10%, unexplained||-!3||*Diarrhea > 1 month, unexplained*'''Oral Candidiasis>10%'''*Oral hairy leukoplakia (EBV-associated)*Acute necrotizing ulcerative stomatitis/gingivitis/periodontitis|*TB, pluribacillary*Bacterial LRIs|*Weight loss >10%, unexplained
|
|-
!4
|
*Herpes simplex infection (oral, genital) > 1 month
*[[Talaromycosis|talaromycosis]] (Asia only)
|
*'''Esophageal Candidiasis'''
*Cryptosporidiasis, chronic
*Isosporiasis, chronic
|
*Pneumocystis pneumonia (PcP)
*TB, paucibacillary
*Severe bacterial LRIs, recurrent
*CNS toxoplamosis (Toxoplasmoma)
*HIV encephalopathy
*CNS cryptococcal infection (Cryptococcoma)
*Progressive multifocal leukoencephalopathy
編集の要約なし
{{TM menuFloating_Menu}}
==疫学==
==WHO Clinical staging==
{{quote|content=[https://apps.who.int/iris/handle/10665/43699 WHO case definitions of HIV for surveillance and revised clinical staging and immunological classification of HIV-related disease in adults and children (2007)]
}}
{|class="wikitable"
|-
!style="width:4%"|Stage
!style="width:24%"|1<br>≈ CD4 500-!style="width:24%"|2<br>≈ CD4 350-500!style="width:24%"|3<br>≈ CD4 200-350!style="width:24%"|4<br>≈ CD4 -200|-style="vertical-align:top"
!Skin
|
|
*Herpes zoster
*Papular pruritic eruptions
*Seborrheic dermatitis
*Fungal nail infections
|
|
*Herpes simplex infection (oral, genital) > 1 month*[[Talaromycosis|Talaromycosis]] (Asia only)|- style="vertical-align:top"
!Oral<br>GI tract
|
|
*Angular cheilitis
*Oral ulcer, recurrent
|
*'''Oral''' candidiasis
*Oral hairy leukoplakia (EBV-associated)
*Acute necrotizing ulcerative stomatitis/gingivitis/periodontitis
*Diarrhea > 1 month, unexplained
|
*'''Esophageal''' candidiasis*Cryptosporidiasis, chronic*Isosporiasis, chronic|-style="vertical-align:top"
!Respiratory
|
|
*URIs, recurrent
|
*Bacterial LRIs
*Pulmonary TB, '''pluribacillary'''
|
*Severe bacterial LRIs, recurrent*Pulmonary TB, '''paucibacillary'''*Pneumocystis pneumonia (PcP)|-style="vertical-align:top"!SystemicNeurological
|
|
|
|
|
*Asymptomatic
*Lymphadenopathy, persistent
|
|
*Fever > 1 month, unexplained
*Sever bacterial infections (LRI, bone/joint infections, meningitis)
*Anemia < 8g/dL of Hb, unexplained
*Thrombocytopenia < 50<math>\times</math>10<math>^9</math>/L, unexplained
|
*HIV wasting syndrome
*Extrapulmonary TB, extrapulmonary
*Cytomegalovirus infection
*Non-typhoidal salmonellosis (NTS), recurrent
*[[Coccidioidomycosis|coccidioidomycosisCoccidioidomycosis]] (America only)*[[Histoplasmosis|histoplasmosisHistoplasmosis]]
*Atypical disseminated leishmaniasis
*HIV-associated nephrophathy
*HIV-associated cardiomyopathy
|- style="vertical-align:top"
!Malignancy
|
|
|
|
*Kaposi's sarcoma
*治療効果判定にはviral load
*CD4 countは初診時には有用だがフォローアップには無用；viral loadが大事
==Additional materials of HIV==
{{quote
|content=[https://www.nature.com/collections/mghkkdjlgx Nature Materials in HIV research]
https://www.nature.com/collections/mghkkdjlgx
}}
