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→12 April 2021
==Epi practicals=====12 April 2021===Is this test useful : Practical - HIV==
*Q1
|}
*Positive predictive value=<math>\frac{316.35}{316.35+13.34}=0.959</math>
*Negative predictive value=<math>\frac{653.66}{1316.3465+653.66}=0.98975</math>
*Q4
*Q6
We should advise the director that donors should be informed to proceed to an additional confirmation test, not just be informed simple positive result.
==Is this test useful: COVID-19 Practical==
*Question 1
{|class="wikitable"
|-
!
!RT-PCR Positive
!RT-PCR Negative
|-
!IgG/M RDT Positive
|91
|6
|-
!IgG/M RDT Negative
|7
|174
|-
!sum
|98
|180
|}
:Sensitivity=<math>\frac{91}{98} = 92.9\%</math>
:Specificity=<math>\frac{174}{180} = 96.7\%</math>
*Question 2
**We should know each figures of positive results of IgG and IgM, because IgG only appears during convalescent period after acute infection and is of little use for bedside diagnosis.
**As well as we still don't know well when IgM appears in blood during acute phase of COVID, which means even IgM RDT may be of little use for bedside diagnosis.
**One more thing we have to be careful is that RT-PCR would show positive for a long period after infection like 2-4 weeks, thus even though RDT shows good sensitivity and specificity compared to RT-PCR collected from asymptomatic persons, RDT results do not necessarily reflect acute phase status.
*Discussion
*Question 3
**(a) No
***Given the prevalence of RT-PCR positive results count 50% of asymptomatic HCWs, why antibody RDT might help to lift self-isolation of mildly symptomatic HCWs .... ? Icouldn't understand what this question wanted to ask.
**(b) No
***Because IgM/G RDT positive results cannot tell whether the patients are in acute or convalescent or post-infection status.
**(c) Partially yes
***If combination of negative IgM and positive IgG truly meant post-infection and guaranteed definite immunity, the RDT could be used for the purpose.
*Question 4
**We still could not have established definite gold or reference standard against acute infection of COVID, so I guess the only possible reference standard against new RT-PCR would be existing RT-PCR.
