「Dermatological mycobacterium infecions」の版間の差分

2021年4月22日 (木) 09:35時点における版

TT direction - abnormal or significant immune response (granulomatous) against few M. leprae bacilli
- PB in WHO classification
- infiltrated plaque
- well-defined, sharp border
- single skin lesion
- localized, asymmetrical
- loss of sensation at skin lesion
  - in histopathology nerves are surrounded by granuloma
LL direction - least cellular immunity or allergic reaction against much amount of M. leprae bacilli
- MB in WHO classification
- macule, papule, nodule

exogenous inoculation
- ulcer,
- tuberculosis verrucosa cutis, warty tuberculosis
- orificial tuberculosis - direct contact of M.t. contained in sputum from pulmonary TB
endogenous spread from internal TB
- abscess,
- scrofuloderma - emerged from lymphadenitis
hematogenous
- nodule, abscess, patch
- as part of miliary tuberculosis
- immunocompromised host, children
tuberculid - allergic reaction against M. tuberculosis
- erythema, papule
- in immunocompetent patient
- skin biopsy of the eruption shows no bacteria
- strong positivity of Mantoux test
- Bazin erythema
  - usually localized to lower legs

@@ 18行目: / 18行目: @@
 ==leprosy==
+*manifests in skin and peripheral nerves
+*papule, macule, plaque, hypopigmentation, nodule
+*loss of sensation, paralysis, amyotrophy
+*incubation months to >30 years
+===Ridley-Jopling classification===
+*TT - tuberculoid
+*BT - borderline tuberculoid
+*BB - borderline borderline
+*BL - borderline lepromatous
+*LL - lepromatous
+*TT direction - abnormal or significant immune response (granulomatous) against few ''M. leprae'' bacilli
+**PB in WHO classification
+**infiltrated plaque
+**well-defined, sharp border
+**single skin lesion
+**localized, asymmetrical
+**loss of sensation at skin lesion
+***in histopathology nerves are surrounded by granuloma
+*LL direction - least cellular immunity or allergic reaction against much amount of ''M. leprae'' bacilli
+**MB in WHO classification
+**macule, papule, nodule
+**
 ==cutaneous TB==