「Amoebiasis」の版間の差分
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| 21行目: | 21行目: | ||
*some encyst in large intestine | *some encyst in large intestine | ||
*cysts are excreted from anus | *cysts are excreted from anus | ||
| + | |||
| + | ===clinical manifestation=== | ||
| + | *incubation a few days to years | ||
| + | *80% of infection are asymptomatic | ||
| + | *mild, extensive, extreme | ||
| + | *large intestine ulcer | ||
| + | **flask-shaped ulcer in histpahology | ||
===morphology=== | ===morphology=== | ||
| 34行目: | 41行目: | ||
**3:1 in developing countries | **3:1 in developing countries | ||
**10:1 in developed countries | **10:1 in developed countries | ||
| + | |||
| + | ==''Entamoeba coli''== | ||
| + | *6 nuclei in cyst | ||
2021年4月27日 (火) 09:42時点における版
目次
Entamoeba histolytica
epidemiology
- worldwide
- 40-50 mil. symptomatic cases per year
- number of asymptomatic cases unknown
- 40,000-50,000 per year
- sexual transmission in developed countries
life cycle and pathophysiology
- feco-oral infection of cyst
- hutch in small intestine into trophozoite
- reside in large intestine
- propagate by binary fission
- some penetrate large intestine wall
- bloody diarrea
- trophozoites phagocityze RBC
- only RBC phagocitizing trophozoite means infection
- non-RBC-phagocitizing trophozoite means colonization
- some invade into portal vein through liver
- liver abscess
- some encyst in large intestine
- cysts are excreted from anus
clinical manifestation
- incubation a few days to years
- 80% of infection are asymptomatic
- mild, extensive, extreme
- large intestine ulcer
- flask-shaped ulcer in histpahology
morphology
- trophozoite 20-50 μm
- cyst has 4 nuclei, each nucleus has a nucleolus
Entamoeba dispar
- formerly named as E. histolytica in 1903
- non-pathogenic type of old E. histolytica was distinguished as E. dispar in 1925
distribution
- E. disper vs E. histolytica
- 3:1 in developing countries
- 10:1 in developed countries
Entamoeba coli
- 6 nuclei in cyst
