「Cryptosporidiosis」の版間の差分
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Vaccipedia.admin (トーク | 投稿記録) (ページの作成:「==''Cryptosporidium'' spp.== *especially ''C. paravum'', ''C. hominis'' ===epidemiology=== *worldwide *2nd important pathogen for moderate-severe diarrhea before 1 year…」) |
Vaccipedia.admin (トーク | 投稿記録) |
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| 5行目: | 5行目: | ||
*worldwide | *worldwide | ||
*2nd important pathogen for moderate-severe diarrhea before 1 year of life | *2nd important pathogen for moderate-severe diarrhea before 1 year of life | ||
| + | *repeated outbreaks even in developed countries with huge number of cases | ||
| + | **human excretes 100 mil. cysts per day | ||
| + | **calf excretes 10 bil. cysts per day | ||
| + | **water chlorination does not prevent tap water borne infection | ||
===life cycle=== | ===life cycle=== | ||
| 12行目: | 16行目: | ||
*survive >1 year in 4-6℃ cold water | *survive >1 year in 4-6℃ cold water | ||
*vulnerable to dry environment | *vulnerable to dry environment | ||
| − | |||
| − | |||
===morphology=== | ===morphology=== | ||
2021年4月27日 (火) 11:26時点における版
目次
Cryptosporidium spp.
- especially C. paravum, C. hominis
epidemiology
- worldwide
- 2nd important pathogen for moderate-severe diarrhea before 1 year of life
- repeated outbreaks even in developed countries with huge number of cases
- human excretes 100 mil. cysts per day
- calf excretes 10 bil. cysts per day
- water chlorination does not prevent tap water borne infection
life cycle
- calf is reservoir of C. hominis
- resistant to chlorinated water
- auto-infection in host intestine
- survive >1 year in 4-6℃ cold water
- vulnerable to dry environment
morphology
- oocyst contains 4 sporozoites
clinical features
- incubation 1-12 days
- symptoms 1-2 weeks
- watery diarrhea
- abd cramps
- bloating
- fever, malaise
- weight loss
- often self-limiting
- problemable in children in developing countries, immunocompromised
diagnosis
- fecal microscopy
- Ziehl-Neelsen stain
- Auramine stain
treatment
- nitazoxianide
- paromomycin
