「Dengue」の版間の差分

提供: Vaccipedia | Resources for Vaccines, Tropical medicine and Travel medicine
ナビゲーションに移動 検索に移動
(ページの作成:「==epidemiology== *70-500 mil. infections per year *2.1 mil. severe dengue per year *21,000 deaths per year *significant impact on both health systems and individuals **no…」)
 
31行目: 31行目:
 
**genotype of dengue virus
 
**genotype of dengue virus
 
**co-morbidity
 
**co-morbidity
 +
 +
==treatment==
 +
*RCTs of antivirals and steroid have shown no effect so far
 +
 +
===algorithm of fluid management===

2021年4月26日 (月) 16:48時点における版

epidemiology

  • 70-500 mil. infections per year
  • 2.1 mil. severe dengue per year
  • 21,000 deaths per year
  • significant impact on both health systems and individuals
    • no reliable way to predict who truely needs hospitalization

clinical course

severe dengue

  • definition WHO
    • warning sign
      • abd pain/tenderness
      • persitent vomiting
      • clinical fluid accumulation
      • mucosal bleeding
      • lethargy
    • severe dengue
      • severe plasma leakage leading to:
      • severe bleeding
      • severe organ involvement
  • dehydration - shock/bleeding - reasbsorption/fluid overload
  • secondary organ impairment may be idiosyncratic
  • risk factors of severe dengue
    • young age
    • female gender
    • previous flavivurs/dengue infection
    • genotype of dengue virus
    • co-morbidity

treatment

  • RCTs of antivirals and steroid have shown no effect so far

algorithm of fluid management

「http://vaccipedia.jp/index.php?title=Dengue&oldid=927」から取得