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**To extrapolate vaccinated animal challenge model
**To extrapolate protective level of dosing of passive immunization (antibody treatment)
 
===Be careful===
*'''"Immune reseponses"''' contain various kinds of immunological functions
**Serum antibodies with multiple isotypes and multiple functions
**Mucosal antibodies with multiple isotypes and multiple functions
**Helper T cells
**Killer T cells
**Regulatory T cells
**etc.

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