「Schistosomiasis」の版間の差分
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*Katsurada Fujiro found 26 May 1904 from a cat in Yamanashi（水腫腸満） | *Katsurada Fujiro found 26 May 1904 from a cat in Yamanashi（水腫腸満） | ||
*Fujinami Kan found 30 May 1904 from a murder victim in Katayama, Hiroshima（片山病） | *Fujinami Kan found 30 May 1904 from a murder victim in Katayama, Hiroshima（片山病） | ||
| − | *found | + | *found egg in 1904 in Saga（奇病） |
| 20行目: | 20行目: | ||
==pathogenesis== | ==pathogenesis== | ||
| − | * | + | *adult female paired by male migrate to messenteric vein from portal vein and lay eggs into messenteric venule, which are secreted from messenteric venule to intestinal lumen |
| − | *inflammation is exclusively due to | + | *eggs also reach urinary bladder or genital tract and generate inflammation, followed by necrosis of tissue and perforation to intestine, resulted in extracorporeal distribution of egg via stool |
| + | *eggs are also distributed in liver and cause inflammation resulting in cirrhosis | ||
| + | *inflammation is exclusively due to egg | ||
*'''adult pairs do not cause disease per se''' | *'''adult pairs do not cause disease per se''' | ||
| + | |||
| + | ==treatment== | ||
| + | *praziquantel was discovered only in mid-1970s in Germany | ||
| + | |||
| + | ==control== | ||
| + | *only way to control is eliminate intermediate hosts, snails | ||
2021年4月19日 (月) 14:08時点における版
目次
schistosoma is distinct from other trematoda
- trematode中schistosomaは他のtrematodeと異なる特徴を持つ
| schistosoma | other trematode |
|---|---|
| transmitted to human by percutaneous invasion of cercariae |
transmitted to human by oral ingestion of metacercariae |
| male and female separated 雌雄別体 | hermaphrodite雌雄同体 |
| does not require 2nd intermediate host (no metacercariae stage) |
requires 2nd intermediate host |
Schistosoma japonicum
- Katsurada Fujiro found 26 May 1904 from a cat in Yamanashi（水腫腸満）
- Fujinami Kan found 30 May 1904 from a murder victim in Katayama, Hiroshima（片山病）
- found egg in 1904 in Saga（奇病）
pathogenesis
- adult female paired by male migrate to messenteric vein from portal vein and lay eggs into messenteric venule, which are secreted from messenteric venule to intestinal lumen
- eggs also reach urinary bladder or genital tract and generate inflammation, followed by necrosis of tissue and perforation to intestine, resulted in extracorporeal distribution of egg via stool
- eggs are also distributed in liver and cause inflammation resulting in cirrhosis
- inflammation is exclusively due to egg
- adult pairs do not cause disease per se
treatment
- praziquantel was discovered only in mid-1970s in Germany
control
- only way to control is eliminate intermediate hosts, snails
