「Giardiasis」の版間の差分
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Vaccipedia.admin (トーク | 投稿記録) (ページの作成:「==''Giardia intestinalis''== *a.k.a. ''G. lamblia'' or ''G. duodenalis'' **「ランブル鞭毛虫」is named after ''G. lamblia'' ===epidemiology=== *worldwide *human…」) |
Vaccipedia.admin (トーク | 投稿記録) |
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| 8行目: | 8行目: | ||
**beaver in North America | **beaver in North America | ||
*water-borne | *water-borne | ||
| + | **food-borne thru uncooked vegetable or fruit washed with contaminated water | ||
| + | *feco-oral | ||
===life cycle=== | ===life cycle=== | ||
| + | *ingestion of cyst | ||
| + | *hutch in intestinal wall into trophozoite | ||
| + | *trophozoite propagets in binary fission | ||
| + | *trophozoite does not invade human cells, just colonize | ||
| + | **produces no bloody diarrhea | ||
| + | *trophozoite transforms into cyst under dry environment | ||
| + | *cyst is resistant to chlorinated water | ||
| + | |||
| + | ===morphology=== | ||
| + | *2 nuclei in trophozoite | ||
| + | *4 nuclei in cyst | ||
| + | |||
| + | ===clinical features=== | ||
| + | *incubation 3 days to months | ||
| + | *10 cysts are enough to develop symptoms | ||
| + | *most asymptomatic | ||
| + | *repeated infections induce immunity | ||
| + | *abrupt onset of diarrhea | ||
| + | *abd cramps | ||
| + | |||
| + | ===diagnosis=== | ||
| + | *fecal microscopy | ||
| + | *duodenal fluid aspiration | ||
| + | **"String test" | ||
| + | **"Crosby capsule" | ||
| + | *antigen detection in feces | ||
| + | **ELISA | ||
| + | **EIA - rapid diagnostic test | ||
| + | *fluorescence microscopy of feces | ||
2021年4月27日 (火) 10:58時点における版
目次
Giardia intestinalis
- a.k.a. G. lamblia or G. duodenalis
- 「ランブル鞭毛虫」is named after G. lamblia
epidemiology
- worldwide
- human is main reservior
- beaver in North America
- water-borne
- food-borne thru uncooked vegetable or fruit washed with contaminated water
- feco-oral
life cycle
- ingestion of cyst
- hutch in intestinal wall into trophozoite
- trophozoite propagets in binary fission
- trophozoite does not invade human cells, just colonize
- produces no bloody diarrhea
- trophozoite transforms into cyst under dry environment
- cyst is resistant to chlorinated water
morphology
- 2 nuclei in trophozoite
- 4 nuclei in cyst
clinical features
- incubation 3 days to months
- 10 cysts are enough to develop symptoms
- most asymptomatic
- repeated infections induce immunity
- abrupt onset of diarrhea
- abd cramps
diagnosis
- fecal microscopy
- duodenal fluid aspiration
- "String test"
- "Crosby capsule"
- antigen detection in feces
- ELISA
- EIA - rapid diagnostic test
- fluorescence microscopy of feces
