Anemia in the tropics

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2021年5月6日 (木) 15:17時点におけるVaccipedia.admin (トーク | 投稿記録)による版
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reference value/cut-off of Hb

  • adjust according to altitude of living

diagnosis

  • POC test kit: HemoCue
  • ferritin increases in inflammation in order to deliver more iron stimulated by inflammation itself as well as to avoid pathogens try to consume iron
  • serum transferrin (TIBC) increases in IDA, decreases in inflammation
  • zinc protoporphyrin (Zpp)
  • soluble transferrin receptor (sTfr)

cause

  • malaria does not cause IDA directly; destruction of RBCs by Plasmodium does not cause iron loss
    • anemia by malaria is mainly by inflammation, which suppresses iron absorption