2,994
回編集
差分
ナビゲーションに移動
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*Asymptomatic
*Acute HIV infection
*Lymphadenopathy, persistent
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!2
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!3
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!4
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*Herpes simplex infection (oral, genital) > 1 month
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*'''Esophageal Candidiasis'''
*TB, paucibacillary
*Cryptosporidiasis, chronic
*Isosporiasis, chronic
*[[Talaromycosis|talaromycosis]] (Asia only)
*[[Coccidioidomycosis|coccidioidomycosis]] (America only)
*[[Histoplasmosis|histoplasmosis]]
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*Pneumocystis pneumonia (PcP)
*Severe bacterial LRIs, recurrent
*CNS toxoplamosis (Toxoplasmoma)
*HIV encephalopathy
*CNS cryptococcal infection (Cryptococcoma)
*Progressive multifocal leukoencephalopathy
編集の要約なし
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==疫学==
==WHO Clinical staging==
{{quote|content=[https://apps.who.int/iris/handle/10665/43699 WHO case definitions of HIV for surveillance and revised clinical staging and immunological classification of HIV-related disease in adults and children (2007)]
}}
{|class="wikitable"
|-
!style="width:54%"|Stage!style="width:1924%"|Skin1<br>≈ CD4 500-!style="width:1924%"|Oral 2<br>& GI tractasymp; CD4 350-500!style="width:1924%"|Respiratory3<br>≈ CD4 200-350!style="width:1924%"|Systemic4<br>≈ CD4 -200!|- style="widthvertical-align:19%top"|Malignancy|-!1||Skin
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*Herpes zoster
*Seborrheic dermatitis
*Fungal nail infections
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*Herpes simplex infection (oral, genital) > 1 month
*[[Talaromycosis|Talaromycosis]] (Asia only)
|- style="vertical-align:top"
!Oral<br>GI tract
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*Angular cheilitis
*Oral ulcer, recurrent
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*'''Oral''' candidiasis
*Oral hairy leukoplakia (EBV-associated)
*Acute necrotizing ulcerative stomatitis/gingivitis/periodontitis
*Diarrhea > 1 month, unexplained
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*'''Esophageal''' candidiasis
*Cryptosporidiasis, chronic
*Isosporiasis, chronic
|- style="vertical-align:top"
!Respiratory
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*URIs, recurrent
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*Weight loss <10%Bacterial LRIs*Pulmonary TB, unexplained'''pluribacillary'''|*Severe bacterial LRIs, recurrent*Pulmonary TB, '''paucibacillary'''*Pneumocystis pneumonia (PcP)|- style="vertical-align:top"!Neurological||
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*CNS toxoplamosis (Toxoplasmoma)
*HIV encephalopathy
*CNS cryptococcal infection (Cryptococcoma)
*Progressive multifocal leukoencephalopathy
|- style="vertical-align:top"
!Systemic
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*Diarrhea > 1 month, unexplainedAsymptomatic*'''Oral Candidiasis'''Acute HIV infection*Oral hairy leukoplakia (EBV-associated)*Acute necrotizing ulcerative stomatitis/gingivitis/periodontitisLymphadenopathy, persistent
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*TBWeight loss '''<10%''', pluribacillary*Bacterial LRIsunexplained
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*Weight loss '''>10%''', unexplained
*Fever > 1 month, unexplained
*Sever bacterial infections (LRI, bone/joint infections, meningitis)
*Anemia < 8g/dL of Hb, unexplained
*Thrombocytopenia < 50<math>\times</math>10<math>^9</math>/L, unexplained
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*HIV wasting syndrome
*Extrapulmonary TB, extrapulmonary
*Cytomegalovirus infection
*Non-typhoidal salmonellosis (NTS), recurrent
*[[Coccidioidomycosis|Coccidioidomycosis]] (America only)
*[[Histoplasmosis|Histoplasmosis]]
*Atypical disseminated leishmaniasis
*HIV-associated nephrophathy
*HIV-associated cardiomyopathy
|- style="vertical-align:top"
!Malignancy
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*Kaposi's sarcoma
*治療効果判定にはviral load
*CD4 countは初診時には有用だがフォローアップには無用；viral loadが大事
==Additional materials of HIV==
{{quote
|content=[https://www.nature.com/collections/mghkkdjlgx Nature Materials in HIV research]
https://www.nature.com/collections/mghkkdjlgx
}}
