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==skin mycobacterial diseases==
*leprosy
*non-TB mycobacterium (NTM)
**water-borne
**''M. ulcerans'' = Buruli ulcer
**''M. chelonae''
**''M. marinum'' - highest incidence
**''M. avium'' - long-maintained hot bath
==when to suspect==
*skin symptoms without '''WITHOUT''' inflammatory sings (pain, swelling, redness)
*slow progression
*specific patient background
**Bazin erythema
***usually localized to lower legs
 
===treatment===
*same as of systemic tuberculosis
 
==skin NTM==
all manifest in similar skin lesions, eruptions
*''M. ulcerans'' = Buruli ulcer
*''M. chelonae''
*''M. marinum'' - highest incidence
**contact with tropical fish
*''M. avium''
**long-maintained hot bath
**hot spring
*''M. peregrinum''
*''M. massiliense'' (''M. abscessus'' subsp. ''massiliense)
 
===treatment===
*use more than two antibiotics to prevent from resistance
*clarithromycin, rifampicin, quinolone, minocycline..
*NO standarized regimen nor treatment duration
 
==Buruli ulcer==
===diagnosis===
*mandatory
**skin manifestation
**histopathology
**PCR
 
*indigenous Buruli ulcer in Japan
**''M. ulcerans'' subsp. ''shinshuense''
*total 76 cases during 1980-2020
*in all age
*[https://www.niid.go.jp/niid/ja/id/838-disease-based/ha/buruli-ulcer.html 感染研:ブルーリ潰瘍]

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