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4. What is the target population and how was it selected? How representative is the population?
*Target population is not clearly mentioned, but it is TB patients possibly in sub-Saharan Africa according to "Introduction" section.
*Sample is selected out of 4 countries in southern Africa, i.e., S Africa, Zimbabwe, Zambia and Tanzania.
*If researchers' target population is sub-Sahara, southern African patients do not necessarily represent the population but might be said as closer.
5. How are exposure variables and outcomes defined?
*
6. Was there potential for misclassification of the outcome?

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