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!!style="width:10em;4em" rowspan="2"|Brand nameYear!style="width:10em;12em"|Approval for childrenPPSV23!style="width:10em;12em"|Introduction to childhood routine immunizationPCV7!style="width:10em;12em"|Approval for adultsPCV13!style="width:10em;12em"|Introduction to adult routine immunization!Note|-!PPSV23|ニューモバックスNP<br>Pneumovax NP|1988（昭和63年）<br>≥ 2 y/o|N/A<sup>†</sup>|1988（昭和63年）|2014（平成26年）<br>only for all 65 y/o or 60-64 with specific conditions<sup>†</sup>|-!PCV7|プレベナー<br>Prevenar|2009（平成21年）|2010（平成22年）|N/A|N/A|Sales terminated and switched to PCV13 in 2013|-!PCV13|プレベナー13<br>Prevenar 13|2013（平成25年）|2013（平成25年）|2014（平成26年）≥ 65 y/o<br>2020（平成28年） people at high risk of IPD irrespective of age|N/A||-!PCV15|バクニュバンス<br>Vaxneuvance|2023（令和5年）|N/A as of 2023|2022（令和4年） people at high risk of IPD irrespective of age|N/A|-!PCV20||Under review as of 2023|||||}†covered by Public Health Insurance for asplenia <nowiki>*</nowiki>Table updated on 24th Aug 2023 {|classstyle="wikitablewidth:12em"|PCV20
<nowiki>*</nowiki>Table updated on 25th Aug 2023
→Effectiveness of pneumococcal vaccines
===History of Pneumococcal vaccines in Japan===
{|class="wikitable"
|+''Table updated on 25th Aug 2023''
|-
|-
!style="width:4em"|Year!style="width:12em"|PPSV23<br>Pneumovax NP!style="width:12em"|PCV7<br>|Prevenar!style="width:12em"|PCV13<br>|Prevenar13!style="width:12em"|PCV15<br>|Vaxneuvance!style="width:12em"|PCV20|
|-
!1988<br>昭和63
|'''Approved '''<br>- 2yr≤<br>'''''Covered for asplenia by Public Health Insurance'''''<br>- Asplenia|| || || || |
|-
!2009<br>平成21
| ||'''Approved'''<br>- 2mo≤ ≤9yr|| || || |
|-
!2010<br>平成22
| ||'''''Routinized'''''<br>- 2mo≤ ≤60mo (<5yr)|| || || |
|-
!2013<br>平成25
| ||'''Terminated ''' and switched to PCV13||'''Approved'''<br>- 2mo≤ <6yr<br>'''''Routinized'''''<br>- 2mo≤ ≤60mo (<5yr)|| || |
|-
!2014<br>平成26
|'''''Routinized'''''<br>- at 65yr<br>or - 60-64yr with specific chronic conditions|| ||'''Approved'''<br>- 65yr≤ at risk of IPD|| || |
|-
!2020<br>令和2
| || ||'''Approved'''<br>- 6yr≤ at risk of IPD|| || |-!2022<br>令和4| || || ||'''Approved'''<br>- elderly<br>- adults at risk of IPD|||-!2023<br>令和5| || || ||'''Approved'''<br>- 2mo≤||''Submitted for approval''|-! !!PPSV23!!PCV7!!PCV13!!PCV15!!PCV20
|}
===Efficacy of pneumococcal vaccines===
===Effectiveness of pneumococcal vaccines===
===Effectiveness against colonization===
==Serotype replacement==
==Overwhelming Post-Splenectomy Infection (OPSI) and pnuemococcus==
