差分

ナビゲーションに移動 検索に移動
733 バイト追加 、 2021年5月30日 (日) 16:47
編集の要約なし
{{TM menu}}
 
==epidemiology==
*endemic >150 countries
==symptoms==
#prodromal symptoms 2-10 days
##itchy, tinglings, numbness around bitten site
#acute neurological period 2-10 days
##furious rabies- 80%
###hydrophobia, aerophobia, hypersalivation, hallucination, high grade fever
##paralytic rabies - 20%
###urinary incontinenceretention →incontinence, constipation###hydrophobia uncommon - difficult to diagnose
##coma to death of 100%
 
*[https://www.youtube.com/watch?v=GI5lW1wp6UU LANCET Rabies 1/3]
*[https://www.youtube.com/watch?v=GbTfdVRxhXs LANCET Rabies 2/3]
*[https://www.youtube.com/watch?v=9A8-CkrvZlQ LANCET Rabies 3/3]
 
==diganosis==
*most of cases are diagnosed postmortem
*history of animal bite
*histology of autopsy-obtained brain specimen
**microscopic observation of Negri body
*immunofluorescnet
*RT-PCR of N gene
 
==prevention==
*PEP
*PreP
 
==control==
*exclusion of straydogs
*establishment of dog registration
*mass vaccination for dogs
 
==JAPOHR Project==
*collaboration with STAREPS Project
*one health approach

案内メニュー