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→disease
*''Histoplasma capsulatum'' var. ''capsulatum''
*soil habitant fungus
*dimorphic fungi
===transmission===
*acute pneumonia
**disseminated consolidations in both lungs
*mediastinal lymphadenopathy
**DDx: TB, sarcoidosis, lymphoma
*chronic lung cavity
**associated with smoking/COPD
**DDx: TB, aspergillosis
*progressive disseminated histoplasmosis
**risk at HIV CD4<150
===diagnosis===
*culture on Sabouraud's agar
**4-8 weeks
*serology
*antigen test in urine
===treatment===
*liposomal amphotericin B
*itraconazole
