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278 バイト追加 、 2021年6月7日 (月) 17:36
*localized (not generalized) tetanus also may occur
*increased muscle tones lasts more than 2 months
*muscle spasm emerges after increased muscle tones and lasts > 1 month**needs long term ventilator support
==diagnosis==
==treatment==
*tetanus immunoglobulin 500 - 1000 IU intramuscular
**only once is needed, to neutralize residual toxins
*penicillin or metronidazole
*spasm management
**muscle relaxants
*tracheostomy and respiratory support
**just to wait washing out of toxin effects
 
*death occurs due to:
**secondary infection by long-term ventilator support
**overwhelming autonomic instability, i.e., cardiovascular death
==prevention==
*wound debridement is crucial
**''C. tetani'' is anaerobe which grows in closed wound area

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