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706 バイト追加 、 2021年6月4日 (金) 15:14
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==History==
*Died from or infected by Tb
*cardiac tamponade
*sequele - carcified pericardium
*very pauci-bacillary and bacterial investigation from pericardiocentesis is very much less sensitive
 
====intestinal====
*can mimic Crohn's disease
*Gene Xpert
**Xpert MTB/RIF
**can detect drug resistantresistance to rifampicin
====histopathology====
**alcohol
**advanced age
*early - 2-3wks, R,H; good prognosis
*late - after 1mo, E; bad prognosis
==Drug-resistant==
===mono-resistant===
*H-resistant approx. 7%
 
*primary resistance
**infected by resistant TB
*secondary resistance
**
 
===multi-resistant MDR===
*resistant to H and R
*risk
**previous Tx
**household contact with MDR
**HIV
*resistance to R is a marker of MDR
**90% of R-resistance strains are also resistant to H → GeneXpert
 
===extensively resistant XDR===
*MDR + fluoroquinolone-resistant and at least one additional group A drug
 
===pre-extensively resistant pre-XDR===
*MDR + fluoroquinolone-resistant

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