「Viral hepatitis」の版間の差分

提供: Vaccipedia | Resources for Vaccines, Tropical medicine and Travel medicine
ナビゲーションに移動 検索に移動
(ページの作成:「==hepatitis virus== *viral hepatitis is 4th major infectious disease worldwide *virus hepatitis is still increasing year by year *>250 mil. people living with viral hepat…」)
 
21行目: 21行目:
  
 
==hep B==
 
==hep B==
*
+
*family ''Hepadonavirus''
 +
*transmission route
 +
**vertical
 +
**horizontal
 +
***sexually transmitted
 +
***sharing needles
 +
===epidemiology===
 +
**240 mil. hep B carriers worldwide
 +
**0.5 mil. death per year
 +
*highly infectious; 10 virus copies are enough to infection
 +
===genotypes===
 +
*genotypes B and C prevalent in Asia
 +
*A in Europe
 +
===acute hep B===
 +
*genotype A is increasing in Japan
 +
**10% of genotype A carrier develope chronic carrier
 +
*6.3% of hep B carrier are co-infected by hep C
 +
===treatment===

2021年4月20日 (火) 13:34時点における版

hepatitis virus

  • viral hepatitis is 4th major infectious disease worldwide
  • virus hepatitis is still increasing year by year
  • >250 mil. people living with viral hepatitis
  • hep B highly prevalent sub-Saharan children <5y/o
  • virus hepatitis has added to one of SDGs in 2016

hep A

  • food-borne, water-borne
  • infection route in Japan
    • mainly by raw oyster in HIV-negative
    • mainly MSM in HIV-positive

hep E

  • water-borne, contaminated meat-borne
    • incompletely cooked deer meat, pig intestine or liver
  • non-enveloped, positive-sense, single-stranded RNA virus
  • endemic in East to Southeast Asia
  • genotype 4 is strongly associated to fluminant hepatitis
  • hep E vaccine has already established in China

hep B

  • family Hepadonavirus
  • transmission route
    • vertical
    • horizontal
      • sexually transmitted
      • sharing needles

epidemiology

    • 240 mil. hep B carriers worldwide
    • 0.5 mil. death per year
  • highly infectious; 10 virus copies are enough to infection

genotypes

  • genotypes B and C prevalent in Asia
  • A in Europe

acute hep B

  • genotype A is increasing in Japan
    • 10% of genotype A carrier develope chronic carrier
  • 6.3% of hep B carrier are co-infected by hep C

treatment