Systematic review and Meta-analysis
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目次
Systematic review
- systematic review vs non-systematic review
- every SR does not have a meta-analysis
- such as Delphi method
strength of SR
weakness of SR
Meta-analysis
- MA does not require SR
network meta-analysis
- to compare efficacy of multiple treatment arms
strength of MA
- overcome publication bias
weakness of MA
conduct SR/MA
- no guidelines on the number of included studies in SR/MA
- Cochrane has published SR/MA with only 1 study included
optimal databases
Bramer WM, et al. Syst Rev. 2017 PMID:29208034
- Medline/PubMed
- Web of Science
- Embase and/or Scopus
- overlapping ratio between Embase and Scopus is very high
- Google Scholar
- grey literature
as many as possible
- grey literatures
- Google Scholar
- New York Academy of Medicine Grey Literature Report
- [SIGLE]
data extraction
- most important and easily mistaken step
