Onchocerciasis

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Onchocerca volvulus

Intermediate host
Category	blackfly ブヨ, female
Latin	genus Simulium
Inward infection	{{{inward}}}
Organ	midgut
Reproduction	{{{reproduction}}}
Course	{{{course}}}
Detection	{{{detection}}}
Outward transmission	{{{outward}}}

Definitive host
Category	HUMAN
Latin
Inward infection	blood-feeding by female blackfly
Organ	skin, lymphatics, blood, urine
Reproduction	sexual
Course	L3 into adult in subcutaneous subcutaneous nodule female 33-50 cm (not mm), male 2-5 cm live 15 years female produce microfilariae 9 years 220-360 µm 2 years mainly skin, sometimes lymphatics, blood, urine
Detection	{{{detection}}}
Outward transmission	{{{outward}}}

診断

• Skin snipping による皮膚断片の培養と顕微鏡下観察
  • 高浸淫地では有用だが，低感度なので有病割合が低下すると有用性が劣る
• RDT
  • Onchocerca vulvolsのIgG4抗体および抗原をimmunochromatographで検出

治療

• Ivermectin

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