「Onchocerciasis」の版間の差分
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Vaccipedia.admin (トーク | 投稿記録) |
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5行目: | 5行目: | ||
|latin=genus ''Simulium'' | |latin=genus ''Simulium'' | ||
|organ=midgut | |organ=midgut | ||
+ | |inward=blood-feeding of human | ||
+ | |reproduction=asexual | ||
+ | |course= | ||
+ | microfilariae has '''no sheath''' | ||
+ | <ol> | ||
+ | <li>migrate to thoracic muscle | ||
+ | <li>metamorphoses L1→L2→L3 in thoracic muscle | ||
+ | <li>L3 migrate to proboscis | ||
+ | </ol> | ||
+ | |detection= | ||
+ | |outward=blood-feeding of human | ||
}} | }} | ||
22行目: | 33行目: | ||
*220-360 µm | *220-360 µm | ||
*2 years | *2 years | ||
− | *mainly skin, sometimes lymphatics, blood, urine | + | *mainly '''skin, connective tissue''', sometimes lymphatics, blood, urine, sputum |
− | * | + | *allergy and inflammation resulting in serious '''skin pruritis (leopard skin, anterior tibia)''' and '''keratitis (river blindeness)''' |
+ | |detection= | ||
+ | <ul> | ||
+ | *'''skin snipping''' | ||
+ | **'''no nocturnality''', every time in a day available | ||
+ | *microfilariae has no sheath | ||
+ | </ul> | ||
+ | |outward=blood-feeding by female blackfly | ||
}} | }} | ||
+ | |||
+ | {{quote|content=[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC100248/ Hall LR, Pearlman E. Pathogenesis of onchocercal keratitis (river blindness). Clin Microbiol Rev. 1999;12(3):445-453. doi:10.1128/cmr.12.3.445]}} | ||
==診断== | ==診断== |
2021年5月27日 (木) 22:59時点における版
Onchocerca volvulus
Intermediate host | |
---|---|
Category | blackfly ブヨ, female |
Latin | genus Simulium |
Inward infection | blood-feeding of human |
Organ | midgut |
Reproduction | asexual |
Course | microfilariae has no sheath
|
Detection | |
Outward transmission | blood-feeding of human |
Definitive host | |
---|---|
Category | HUMAN |
Latin | |
Inward infection | blood-feeding by female blackfly |
Organ | skin, lymphatics, blood, urine |
Reproduction | sexual |
Course |
|
Detection |
|
Outward transmission | blood-feeding by female blackfly |
診断
- Skin snipping による皮膚断片の培養と顕微鏡下観察
- 高浸淫地では有用だが,低感度なので有病割合が低下すると有用性が劣る
- RDT
- Onchocerca vulvolsのIgG4抗体および抗原をimmunochromatographで検出
治療
- Ivermectin