「Keys for Tropical Medicine 1」の版間の差分
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**Lower respiratory infections | **Lower respiratory infections | ||
**Diarrhea | **Diarrhea | ||
+ | }} | ||
+ | |||
+ | ==Virus== | ||
+ | {{collapse | ||
+ | |title= | ||
+ | '''Two major classification manners of viruses''' | ||
+ | |content= | ||
+ | *RNA virus vs DNA virus | ||
+ | *Enveloped virus vs Non-enveloped virus | ||
+ | }} | ||
+ | |||
+ | {{collapse | ||
+ | |title= | ||
+ | '''Diagnostic methods of virus infection''' | ||
+ | |content= | ||
+ | *Detection of pathogen | ||
+ | **Genome detection by PCR and other NAATs (nucleic acid amplification tests) | ||
+ | **Antigen detection by ELISA and immunochromatography, etc. | ||
+ | **Virus isolation using human/animal cells | ||
+ | *Detection of antibody | ||
+ | **IgM or IgG by ELISA and immunochromatography, etc. | ||
+ | **Neutralizing antibody using human/animal cells | ||
+ | }} | ||
+ | |||
+ | {{collapse | ||
+ | |title= | ||
+ | '''Definition of arboviruses''' | ||
+ | |content= | ||
+ | }} | ||
+ | |||
+ | {{collapse | ||
+ | |title= | ||
+ | '''Classification of major arboviruses and their major vectors''' | ||
+ | |content= | ||
+ | }} | ||
+ | |||
+ | {{collapse | ||
+ | |title= | ||
+ | '''Warning signs of severe dengue''' | ||
+ | |content= | ||
+ | }} | ||
+ | |||
+ | {{collapse | ||
+ | |title= | ||
+ | '''List of Vaccine-preventable arbovirus infections''' | ||
+ | |content= | ||
+ | }} | ||
+ | |||
+ | {{collapse | ||
+ | |title= | ||
+ | '''Essential knowledge of HIV''' | ||
+ | |content= | ||
+ | [https://drive.google.com/file/d/1N5GBSimejHLEk9We-fEC240mgjuT5-PC/view?usp=share_link Watch our Group 4 video and pick up information described in blue letters!] | ||
}} | }} | ||
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{{collapse | {{collapse | ||
|title= | |title= | ||
− | ''' | + | '''Classification of major Gram-Positive cocci''' |
+ | |content= | ||
+ | <table border="1" style="border-collapse:collapse"> | ||
+ | <tr bgcolor="lightgray"> | ||
+ | <th rowspan="2" bgcolor="lightgray">Catalase Positive<br>in tubes</th> | ||
+ | <th colspan="3">Coagulase Positive<br>in tubes</th> | ||
+ | <th colspan="3">Coagulase Negative<br>in tubes</th> | ||
+ | </tr> | ||
+ | |||
+ | <tr> | ||
+ | <td colspan="3"> | ||
+ | *''Staphylococcus aureus'' | ||
+ | </td> | ||
+ | <td colspan="3"> | ||
+ | *''Staphylococcus epidermidis'' | ||
+ | *''Staphylococcus saprophyticus'' | ||
+ | </td> | ||
+ | </tr> | ||
+ | |||
+ | <tr bgcolor="lightgray"> | ||
+ | <th rowspan="2" bgcolor="lightgray">Catalase Negative<br>in tubes</th> | ||
+ | <th colspan="2">α hemolytic<br>(partial hemolysis)<br>on media</th> | ||
+ | <th colspan="2">β hemolytic<br>(complete hemolysis)<br>on media</th> | ||
+ | <th colspan="2">γ hemolytic<br>(no hemolysis)<br>on media</th> | ||
+ | </tr> | ||
+ | </tr> | ||
+ | |||
+ | <tr> | ||
+ | <td colspan="2"> | ||
+ | *''Streptococcus pneumoniae'' | ||
+ | *''Streptococcus suis'' | ||
+ | *viridans ''Streptococcus'' | ||
+ | </td> | ||
+ | <td colspan="2"> | ||
+ | *Group A (beta) streptococci (''Streptococcus pyogenes'') | ||
+ | *Group B (beta) streptococci (''Streptococcus agalactae'') | ||
+ | *Group C (beta) streptococci | ||
+ | *Group G (beta) streptococci | ||
+ | </td> | ||
+ | <td colspan="2"> | ||
+ | *''Streptococcus bovis'' | ||
+ | *''Enterococcus faecium'' | ||
+ | *''Enterococcus faecalis'' | ||
+ | </td> | ||
+ | </tr> | ||
+ | </table> | ||
+ | }} | ||
+ | |||
+ | {{collapse | ||
+ | |title= | ||
+ | '''Classification of major Gram-Positive bacilli''' | ||
|content= | |content= | ||
− | + | <table border="1" style="border-collapse:collapse"> | |
− | + | <tr bgcolor="lightgray"> | |
− | + | <th></th> | |
− | + | <th>Spore forming</th> | |
− | + | <th>Non-spore forming</th> | |
− | + | </tr> | |
− | + | ||
− | + | <tr> | |
− | + | <th bgcolor="lightgray">Aerobic</th> | |
− | + | <td> | |
− | + | *''Bacillus anthracis'' | |
− | + | *''Bacillus cereus'' | |
− | + | </td> | |
− | + | <td> | |
− | + | *''Corynebacterium diphtheria'' | |
− | * | + | </td> |
− | * | + | </tr> |
− | + | ||
− | + | <tr> | |
− | + | <th bgcolor="lightgray">Anaerobic</th> | |
− | + | <td> | |
− | + | *''Clostridium tetani'' | |
− | + | *''Clostridium perfringens'' | |
+ | </td> | ||
+ | <td> | ||
+ | *''Listeria monocytogenes'' | ||
+ | </td> | ||
+ | </tr> | ||
+ | </table> | ||
}} | }} | ||
{{collapse | {{collapse | ||
|title= | |title= | ||
− | ''' | + | '''Classification of major Gram-Negative cocci''' |
|content= | |content= | ||
− | + | <table border="1" style="border-collapse:collapse"> | |
− | * | + | <tr> |
− | ** | + | </tr> |
− | ***'' | + | |
− | ***'' | + | <tr> |
− | ** | + | </tr> |
− | ***'' | + | |
− | ***'' | + | <tr> |
− | * | + | </tr> |
− | ** | + | |
− | ***'' | + | </table> |
− | ** | + | |
− | ***'' | + | }} |
+ | |||
+ | {{collapse | ||
+ | |title= | ||
+ | '''Classification of major Gram-Negative bacili''' | ||
+ | |content= | ||
+ | <table border="1" style="border-collapse:collapse"> | ||
+ | <tr> | ||
+ | <th bgcolor="lightgray">Lactose fermenting</th> | ||
+ | <td> | ||
+ | *''Escherichia coli'' | ||
+ | *''Klebsiella pneumoniae'' | ||
+ | </td> | ||
+ | </tr> | ||
+ | |||
+ | <tr> | ||
+ | <th bgcolor="lightgray">Non-lactose fermenting</th> | ||
+ | <td> | ||
+ | *''Shigella'' spp. | ||
+ | *''Salmonella'' spp. | ||
+ | *''Yersinia pestis'' | ||
+ | </td> | ||
+ | </tr> | ||
+ | |||
+ | <tr> | ||
+ | <th bgcolor="lightgray">Non-fermenting</th> | ||
+ | <td> | ||
+ | *''Pseudomonas aeruginosa'' | ||
+ | *''Burkholderia pseudomallei'' | ||
+ | </td> | ||
+ | </tr> | ||
+ | |||
+ | </table> | ||
+ | }} | ||
+ | |||
+ | {{collapse | ||
+ | |title= | ||
+ | '''Essential knowledge of Tuberculosis''' | ||
+ | |content= | ||
+ | *Bacterial structure different from other major bacteria | ||
+ | **Too thick lipid-rich cell wall; acid fast | ||
+ | *Epidemiology and disease burden | ||
+ | *Three species causing clinical tuberculosis | ||
+ | **''Mycobacterium tuberculosis'' | ||
+ | **''M. bovis'' | ||
+ | **''M. africanum'' (only in Africa) | ||
+ | *Airborne transmission | ||
+ | **No contact/fomite transmission | ||
+ | **Contaminated milk ingestion may cause food-borne tuberculosis by ''M. bovis'' (''bovis'' means cow) | ||
+ | *Three major Symptoms | ||
+ | **Cough for weeks | ||
+ | **Weight loss for weeks | ||
+ | **Night sweats for weeks | ||
+ | *Diagnostic methods | ||
+ | **sputum microscopy (Ziel-Nielsen staining) | ||
+ | **genome detection by GeneXpert (also detects resistance) | ||
+ | **culture (6-8 weeks) | ||
+ | **chest X-ray | ||
+ | **urine LAM assay | ||
+ | **Mantoux test and IGRA for latent infection | ||
+ | *Potential of long-term (months, years to decades) infection | ||
+ | **Human immune system cannot eliminate established infection but only contains (just to 'hide' ''Mycobacterium'') | ||
+ | *HIV-Tb co-infection is soooooo major public health problem | ||
+ | *Treatment | ||
+ | **6 months (2 intensive + 4 maintenance) | ||
+ | *Definition of drug resistance | ||
+ | **MDR | ||
+ | **XDR | ||
+ | }} | ||
+ | |||
+ | ==Protozoa== | ||
+ | {{collapse | ||
+ | |title= | ||
+ | '''How protozoa differ from bacteria''' | ||
+ | |content= | ||
+ | }} | ||
+ | |||
+ | {{collapse | ||
+ | |title= | ||
+ | '''Classification of major protozoa in terms of reproduction manners and infecting organs/cells''' | ||
+ | |content= | ||
+ | -> [[Overview_of_protozoa]] | ||
+ | }} | ||
+ | |||
+ | {{collapse | ||
+ | |title= | ||
+ | '''Essential knowledge of malaria''' | ||
+ | |content= | ||
+ | *Epidemiology and disease burden of malaria worldwide | ||
+ | **Especially of ''Plasmodium falciparum'' | ||
+ | *Essential lifecycle | ||
+ | #Mosquito stage | ||
+ | #Human liver stage | ||
+ | #Human red cell stage | ||
+ | *Only ''P. vivax'' and ''P. ovale'' have hypnotic stage in liver cause '''relapse''' | ||
+ | **All species cause '''recrudescence''' due to inadequate/improper treatment | ||
+ | *Fever, Anemia, Splenomegaly | ||
+ | *Cerebral malaria almost only by ''P. falciparum'', which leads to high mortality | ||
+ | *Diagnosis made by Rapid Diagnostic Test (RDT) and Blood smear microscopy (Giemsa staining) | ||
+ | **Blood smear includes thick smear (just to detect ''Plasmodium'') and thin smear (confirm species of ''Plasmodium'' and degree of parasitemia as disease severity) | ||
+ | }} | ||
+ | |||
+ | ==Parasite== | ||
+ | {{collapse | ||
+ | |title= | ||
+ | '''Major classification of parasites''' | ||
+ | |content= | ||
+ | *Helminth | ||
+ | **Nematode (round worm) | ||
+ | **Trematode (fluke, distoma) | ||
+ | **Cestode (tape worm) | ||
+ | *Ectoparasite | ||
+ | }} | ||
+ | |||
+ | ==Zoonosis== | ||
+ | {{collapse | ||
+ | |title= | ||
+ | '''Definition of Zoonosis''' | ||
+ | |content= | ||
+ | }} | ||
+ | |||
+ | {{collapse | ||
+ | |title= | ||
+ | '''List of major zoonoses and their host animals''' | ||
+ | |content= | ||
+ | <table border="1" style="border-collapse:collapse"> | ||
+ | <tr bgcolor="lightgray"> | ||
+ | <th></th> | ||
+ | <th>Disease</th> | ||
+ | <th>Pathogen</th> | ||
+ | <th>Host animals</th> | ||
+ | </tr> | ||
+ | |||
+ | <tr> | ||
+ | <th rowspan="4" bgcolor="lightgray">Virus</th> | ||
+ | <td>Ebola virus disease</td> | ||
+ | <td>Ebolavirus</td> | ||
+ | <td>Fruit bat</td> | ||
+ | </tr> | ||
+ | |||
+ | <tr> | ||
+ | <td>Marburg disease</td> | ||
+ | <td>Marburg virus</td> | ||
+ | <td>Fruit bat</td> | ||
+ | </tr> | ||
+ | |||
+ | <tr> | ||
+ | <td>Middle East Respiratory Syndrome (MERS)</td> | ||
+ | <td>MERS coronavirus</td> | ||
+ | <td>Camel <- Bat?</td> | ||
+ | </tr> | ||
+ | |||
+ | <tr> | ||
+ | <td>Severe Fever with Thrombocytopenia Syndrome (SFTS)</td> | ||
+ | <td>SFTS virus</td> | ||
+ | <td>Deer, wild bores</td> | ||
+ | </tr> | ||
+ | |||
+ | <tr> | ||
+ | <th bgcolor="lightgray">Bacteria</th> | ||
+ | <td>Anthrax</th> | ||
+ | <td>''Bacillus anthracis''</td> | ||
+ | <td>Herbivore (cattle, sheep, goat) | ||
+ | </table> | ||
}} | }} |
2022年12月5日 (月) 23:45時点における最新版
Overview of Tropical Medicine
Definition of the tropics
Top 3 causes of death in LMICs, HICs and worldwide in 2016
Changes of top 10 causes of death worldwide from 2010 to 2016
List Neglected Tropical Diseases (NTDs) and what are not listed as NTDs
Virus
Two major classification manners of viruses
Diagnostic methods of virus infection
Definition of arboviruses
Classification of major arboviruses and their major vectors
Warning signs of severe dengue
List of Vaccine-preventable arbovirus infections
Essential knowledge of HIV
Bacteria
Biological basis of Gram staining
Classification of major Gram-Positive cocci
Classification of major Gram-Positive bacilli
Classification of major Gram-Negative cocci
Classification of major Gram-Negative bacili
Essential knowledge of Tuberculosis
Protozoa
How protozoa differ from bacteria
Classification of major protozoa in terms of reproduction manners and infecting organs/cells
Essential knowledge of malaria
Parasite
Major classification of parasites
Zoonosis
Definition of Zoonosis
List of major zoonoses and their host animals