Vaccines for Asplenia

UPDATE HISTORY

• This page was created at 15th Feb 2023

Vaccines specifically recommended for asplenia

Haemophillus influenzae type b (Hib) vaccine

Pneumococcal vaccines

Meningococcal vaccines

Interaction between meningococcal and pneumococcal conjugate vaccine

See Interactions of MenACWY conjugate vaccines and other vaccines

Immunization schedules for asplenia

※NOTICE

• The following descriptions are based on Official Routine Immunization Schedules in Japan as well as vaccines approvement in Japan.
• Catch-up schedules not covered by Official Schedules in Japan are derived from ACIP recommendations for Altered Immunocompetence and Catch-up Immunization Schedule for Children and Adolescents Who Start Late or Who Are More than 1 Month Behind.
  • both accessed on 15th Feb 2023

Catch-up schedules for asplenia with unimmunized for each of vaccine

Age	Hib if unimmunized	Pneumococcal if unimmunized	Meningococcal if unimmunized
years < 2	Immunize according to Official Routine Schedules	PCV13: 2-3 doses according to Official Routine Schedules PPSC23: wait until ≥ 2 years old	Wait until ≥ 2 years old
2 ≤ years < 5	Immunize according to Official Catchup Schedules	PCV13: 2 doses [0, 8w], of which 1 dose as Official Catchup Schedules PPSV23: 2 doses [0, 5y] 8 weeks after the last PCV13
5 ≤ years < 6		PCV13: 1 dose as Official Catchup Schedules PPSV23: 2 doses [0, 5y] 8 weeks after the last PCV13
6 ≤ years < 64		PCV13: 1 dose PPSV23: 2 doses [0, 5y] 8 weeks after the last PCV13
65 ≤ years

Before a scheduled splenectomy

Post-splenectomy and congenital asplenia