Vaccines for Asplenia

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UPDATE HISTORY

• This page was created at 15th Feb 2023

Vaccines specifically recommended for asplenia

Interaction between meningococcal and pneumococcal conjugate vaccine

See Interactions of MenACWY conjugate vaccines and other vaccines

Immunization schedules for asplenia

※NOTICE

• The following descriptions are based on Official Routine Immunization Schedules in Japan as well as vaccines approvement in Japan.
• Catch-up schedules not covered by Official Schedules in Japan are derived from ACIP recommendations for Altered Immunocompetence and Catch-up Immunization Schedule for Children and Adolescents Who Start Late or Who Are More than 1 Month Behind (both accessed on 15th Feb 2023).

Catch-up schedules for asplenia with unimmunized for each of vaccine

Age	Hib if unimmunized	Pneumococcal if unimmunized	Meningococcal if unimmunized	Age
years < 1	3-4 Hib as Official Routine Schedules	3-4 PCV13 as Official Routine Schedules PPSV23: wait until ≥ 2 years old	Wait until ≥ 2 years old consider unapproved imported MenACWY-CRM	years < 1
1 ≤ years < 2	2 Hib [0, 8w] of which 1 dose as Official Catch-up Schedules	2 PCV13 [0, 60d] as Official Routine Schedules PPSV23: wait until ≥ 2 years old		1 ≤ years < 2
2 ≤ years < 5	2 Hib [0, 8w]	2 PCV13 [0, 8w] of which 1 dose as Official Catch-up Schedules if PPSV23 precedes, 1 year after the precedent PPSV23 2 PPSV23 [0, 5y] 8 weeks after the last PCV13	2 Men-ACWY [0, 8w] メナクトラ Menactra exclusively 4 weeks after PCV13 メンクアッドフィ MenQuadfi can be co-administered with PCV13	2 ≤ years < 5
5 ≤ years < 6	1 Hib	1 PCV13 as Official Catch-up Schedules if PPSV23 precedes, 1 year after the precedent PPSV23 2 PPSV23 [0, 5y] 8 weeks after the last PCV13		5 ≤ years < 6
6 ≤ years <10		1 PCV13 if PPSV23 precedes, 1 year after the precedent PPSV23 2 PPSV23 [0, 5y] 8 weeks after the last PCV13		6 ≤ years <10
10 ≤ years			2 Men-ACWY [0, 8w] メナクトラ Menactra exclusively 4 weeks after PCV13 メンクアッドフィ MenQuadfi can be co-administered with PCV13 consider unapproved imported Men-B	10 ≤ years