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- ヒト体内でadultから生まれたmicrofilariaは吸血で蚊に移行し,蚊の体内で3回moltを繰り返してL3 larvaeに至る.
- L3は1.7mmまで体長を増し,吸血によって蚊の体外に放出され,蚊が生じた穿刺口等から皮内に侵入する
- 1.7mmもの体長のlarvaeがどうやって体長10mmに満たない蚊の体内で共存できるのか?
- Onchocerciasisのヒト体内の病態生理はmicrofilariaによるが,lymphatic filariasisはadultによる.
- Lymphatic filariasisでリンパ浮腫を生じている患者の下肢をエコーで観察すると,拡張したリンパ管内で蠢くadult filariaを観察できる.
Brugia malayi
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Paratenic host
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Definitive host
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Dead-end host
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