差分

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**'''ivermectin ''' is effective '''only for microfilariae'''**only one dose of ivermectin 150 µg/kg (both for children and adults) significantly decrease microfilariae load that '''lasts a year or more'''**'''every 6 month repetition'''*If use diethylcarbamazepine (DEC) for onchocerciasis it kills microfilariae inside skin and develops severe allergic reaction against dead microfilariae on skin

**'''doxycycline ''' is effective for '''''Wolbachia''''' resulting in '''killing of 60% and sterlizing 80-90% of female adult'''