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===weakness of MA===
 
==conduct SR/MA==
*no guidelines on the number of included studies in SR/MA
*Cochrane has published SR/MA with only 1 study included
 
===optimal databases===
Bramer WM, et al. Syst Rev. 2017 PMID:29208034
*Medline/PubMed
*Web of Science
*Embase and/or Scopus
**overlapping ratio between Embase and Scopus is very high
*Google Scholar
**grey literature
as many as possible
 
*grey literatures
**Google Scholar
**New York Academy of Medicine Grey Literature Report
**[[https://en.wikipedia.org/wiki/System_for_Information_on_Grey_Literature_in_Europe SIGLE]]
 
===data extraction===
*most important and easily mistaken step

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