Systematic review and Meta-analysis

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Systematic review

  • systematic review vs non-systematic review
  • every SR does not have a meta-analysis
    • such as Delphi method

strength of SR

weakness of SR

Meta-analysis

  • MA does not require SR

network meta-analysis

  • to compare efficacy of multiple treatment arms

strength of MA

  • overcome publication bias

weakness of MA

conduct SR/MA

  • no guidelines on the number of included studies in SR/MA
  • Cochrane has published SR/MA with only 1 study included