Vaccines for Asplenia

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UPDATE HISTORY

  • This page was created at 15th Feb 2023

Function of spleen against specific pathogens

Serious infections under apslenic condition

Vaccines specifically recommended for asplenia

Haemophillus influenzae type b (Hib) vaccine

Pneumococcal vaccines

Meningococcal vaccines

Interaction between meningococcal and pneumococcal conjugate vaccine

See Interactions of MenACWY conjugate vaccines and other vaccines

Immunization schedules for asplenia

※NOTICE

Catch-up schedules for asplenia with unimmunized for each of vaccine
Age Hib if unimmunized Pneumococcal if unimmunized Meningococcal if unimmunized Age
years < 1
  • 3-4 Hib as Official Routine Schedules
  • 3-4 PCV13 as Official Routine Schedules
  • PPSV23: wait until ≥ 2 years old
  • Wait until ≥ 2 years old
    • consider unapproved imported MenACWY-CRM
years < 1
1 ≤ years < 2
  • 2 Hib [0, 8w]
    • of which 1 dose as Official Catch-up Schedules
  • 2 PCV13 [0, 60d] as Official Routine Schedules
  • PPSV23: wait until ≥ 2 years old
1 ≤ years < 2
2 ≤ years < 5
  • 2 Hib [0, 8w]
  • 2 PCV13 [0, 8w]
    • of which 1 dose as Official Catch-up Schedules
    • if PPSV23 precedes, 1 year after the precedent PPSV23
  • 2 PPSV23 [0, 5y]
    • 8 weeks after the last PCV13
2 ≤ years < 5
5 ≤ years < 6
  • 1 Hib
  • 1 PCV13 as Official Catch-up Schedules
    • if PPSV23 precedes, 1 year after the precedent PPSV23
  • 2 PPSV23 [0, 5y]
    • 8 weeks after the last PCV13
5 ≤ years < 6
6 ≤ years <10
  • 1 PCV13
    • if PPSV23 precedes, 1 year after the precedent PPSV23
  • 2 PPSV23 [0, 5y]
    • 8 weeks after the last PCV13
6 ≤ years <10
10 ≤ years 10 ≤ years


Before a scheduled splenectomy

Post-splenectomy and congenital asplenia