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*At clinical trial of Menactra
*Doses at 9 and 12 months of age
*Concomitant dose with PCV7 at 12 months showed unmet non-inferiority criteria in 3 pneumococcal serotypes out of 7 in PCV7
→Interactions of MenACWY conjugate vaccines and other vaccines
{|class="wikitable"
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!rowspan="2"| !!MenACWY-DT!*conjugated with diphtheria toxoid*メナクトラ Menactra!MenACWY-TT|-*conjugated with tetanus toxoid!メナクトラ Menactra!!*メンクアッドフィ MenQuadfi
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!PCV7
*conjugated with DT
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*In a clinical trial of Menactra<sup>1)</sup>
*Concomitant administration of Menactra+PCV7 at 12 months of age showed '''unmet non-inferiority criteria of pneumococcal IgG in 3 serotypes''' out of 7 in PCV7
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!PCV13
*conjugated with DT
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*MenQuadfi+PCV13 can be administered concomitantly<sup>2)</sup>, though SBA of serogroup A was lower of unknown clinical relevance
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!Td
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*In an RCT<sup>1)</sup>
*Serum bactericidal assay (SBA) titers of serogroups C, W and Y in 11-17 years of age were '''higher in concomitant administration of Menactra+Td''' than single Menactra
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!DTaP
*containing DT & TT
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*In an RCT<sup>1)</sup>
*SBA titers of all 4 serogroups in 4-6 years of age were '''lower in [DTaP (DAPTACEL) -> 30days -> Menactra]''' than in [Menactra -> 30days ->DTaP (DAPTACEL)]
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!Tdap
*containing DT & TT
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*MenQuadfi+Tdap can be administered concomitantly<sup>2)</sup>, though amongst pertussis antigens of PT, FHA, PRN and FIM, antibody titer against PT was non-inferior, whereas titers against FHA, RPN and FIM were lower, with unknown clinical relevance
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{{quote|content=
*1) [https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4d8781ff-9366-462c-8161-6e958f44fcb4 14.3 Concomitant Vaccine Administration, Drug LabelInformation, MENACTRA. DailyMed, National Library of Medicine] (last accessed 15th Feb 2023)
*2) [https://www.ema.europa.eu/documents/product-information/menquadfi-epar-product-information_en.pdf 4.5 Interaction with other medicinal products and other forms of interaction, MenQuadfi:EPAR-Product information, European Medicines Agency] (last accessed 15th Feb 2023)
}}
