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*ヒト体内でadultから生まれたmicrofilariaは吸血で蚊に移行し,蚊の体内で3回moltを繰り返してL3 larvaeに至る.
*
[https://www.youtube.com/watch?v=daLr_clpaso Filarial dance under ultrasonography]
 
==distribution==
[[file:Lymphatic Filariasis distribution 2006.jpg|500px]]
 
==''Brugia malayi''==
{{intermediate
|latin=
|inward=blood-feeding by mosquito
|organ=skinlymphatics, lymphaticsblood stream
|reproduction=sexual
|course=
*obstruct lymphatics resulted in '''elephantiasis''' and '''hydrocele''' in years
<li>mate in lymphatics
<li>produce '''sheathed microfilariae'''(no egg)
*177-230 µm
*nocturnal periodicity
|latin=
|inward=blood-feeding by mosquito
|organ=skinlymphatics, lymphaticsblood stream
|reproduction=sexual
|course=
*obstruct lymphatics resulted in '''elephantiasis''' and '''hydrocele''' in years
<li>mate in lymphatics
<li>produce '''sheathed microfilariae'''(no egg)
*244-296 µm
*nocturnal periodicity
<ul></ul>
*'''microscopy''', '''microfilariae''', Giemsa stain, blood taken nocturnally
**concentration technique***2% formalin to blood (Knott's technique)***polycarbonate membrane filtration*blood Ag RDT; rapid immunochromatographic '''antigen''' test (ICT card test)*urine Ab ELISA; high sensitivity and specificity**possible diurnally
|outward=blood-feeding by mosquito
}}
==mass drug administration MDA==*'''Diethylcarbamazepine (DEC) 6mg/kg only once''' for all inhabitant in endemic area**repeated several consecutive years{{DTMHhomequote|content=[http://doi.org/10.1371/journal.pntd.0000317 Ottesen EA, Hooper PJ, Bradley M, Biswas G. The global programme to eliminate lymphatic filariasis: Health impact after 8 years. PLoS Negl Trop Dis. 2008;2(10). doi:10.1371/journal.pntd.0000317]}}

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