Paracoccidioidomycosis

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Pathogen

• Paracoccidioides brasiliensis
• P. lutzii
• dimorphic fungus
• incubation years even more decades
• natural habitat unknown
  • almadillo known resorvoir
• petri dish culture shows very specific appearance
  • culture takes long time more than 4 weeks
• pilot's wheel or steering wheel appearance under microscopy of yeast form because of spore budding

Distribution

• only in South America
  • Brasil, Venezuela, Columbia

Clinical features

• pulmonary
• lymphadenitis
• may disseminate to skin and mucosa

Diagnosis

• pathology with pilot's wheel yeast
• serology

Treatment

• no spontaneous relief
• should absolutely be treated
• AMPH-B, azoles
• less mortal