Tularaemia

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pathogen

• Francisella tularensis

epidemiology

• widespread throughout Northern Hemisphere

transmission

• tick bite by Ixodes
• aspiration of aerosolized pathogen
• ingestion of contaminated food and water
• close contact with infected animals

clinical

• Type A
  • fatal
• Type B
  • ulcerograndular
    • entry site's lymphadenopathy ± skin ulcers
  • ocular
    • conjunctivitis with pain and purulent discharge
  • oropharyngeal
    • pharyngitis, GI bleeding
  • pneumonitis
    • when aspirate aerosolized Francisella
    • necrotizing
  • septicemia

treatment

• gentamycin
• doxycycline