「Pneumococcus」の版間の差分
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10行目: | 10行目: | ||
*all serotypes known more than 90 are pathogenic for human | *all serotypes known more than 90 are pathogenic for human | ||
*differentiation of serotypes is important for epidemiology | *differentiation of serotypes is important for epidemiology | ||
+ | |||
+ | ==antimicrobial resitance== | ||
+ | *first reported in late 1960s | ||
+ | |||
+ | ==vaccine== | ||
+ | *PPSV does not induce T-cell dependent immunity | ||
+ | *PCV induces T-cell dependent immunity | ||
+ | *why PPSV still has efficacy in older population while PCV couldn't show higher efficacy than PCV for older population? | ||
+ | *new product "Pneumosil" from India | ||
+ | **10-valent | ||
+ | **serotypes 1, 5, 6A, 6B, 7F, 9V, 14, 19A, 19F, 23F |
2021年5月31日 (月) 13:51時点における版
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epidemiology
- 1.19mi. deaths in 2016
- 197.05 mil. episodes in 2016
- the leading cause of lower respiratory infections followed by H. influenzae, influenza /B and RS virus
- 50% of pneumococcal deaths in India, Nigeria, DRC and Pakistan
serotype
- all serotypes known more than 90 are pathogenic for human
- differentiation of serotypes is important for epidemiology
antimicrobial resitance
- first reported in late 1960s
vaccine
- PPSV does not induce T-cell dependent immunity
- PCV induces T-cell dependent immunity
- why PPSV still has efficacy in older population while PCV couldn't show higher efficacy than PCV for older population?
- new product "Pneumosil" from India
- 10-valent
- serotypes 1, 5, 6A, 6B, 7F, 9V, 14, 19A, 19F, 23F