Brucellosis

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pathogen

• Brucella aboutus
  • cattle
  • Africa, temperate zone
• B. melitensis
  • goats, sheep, camels
  • Mediterranean, Middle East, Americas
• B. suis
  • pigs, reindeer, rodents
  • USA and everywhere
• B. canis
  • dogs

• gram negative cocco-bacilli
• facultative intracellular bacteria

clinical features

• transmission
  • ingestion of contaminated unpasteurised milk, soft cheese, natural cheese
  • aspiration of infected dust
    • farmers and vets higher risk
  • animal contact
  • human-to-human extremely rare
• incubation 1 week to weeks to months
• HIV not risk factor
• flu-like illness
  • fever undulating and lasts for weeks
  • night sweats
  • dry cough
• myalgia and arthralgia
  • difficulty walking
• depressive, anorexic, lethargy
• hepatosplenomegaly