「Tetanus」の版間の差分
ナビゲーションに移動
検索に移動
Vaccipedia.admin (トーク | 投稿記録) (ページの作成:「{{TM menu}} ==pathogen== ==epidmiology== ==clinical picture== ==diagnosis== ==treatment==」) |
Vaccipedia.admin (トーク | 投稿記録) |
||
| 2行目: | 2行目: | ||
==pathogen== | ==pathogen== | ||
| + | *''Clostridium tetani'' | ||
| + | *gram positive terminal round shape (drumstick like) bacilli | ||
| + | *spore-forming | ||
| + | **drumstick looking is from spore | ||
| + | **means long term sustainability in soil | ||
| + | *strict anaerobe | ||
| + | *incubation 3-21 days (average 10 days) | ||
| + | *AB toxin | ||
| + | **blockade of releasing GABA in synapus | ||
| + | **convulsive contraction of voluntary muscles | ||
| + | **toxin binding is irreversible | ||
==epidmiology== | ==epidmiology== | ||
==clinical picture== | ==clinical picture== | ||
| + | *opisthotonus | ||
| + | **muscle spasm in opisthotonus is very painful | ||
| + | *trismus (lockjaw) | ||
| + | **difficulty opening mouth | ||
| + | *respiratory difficulties | ||
| + | *cardiovascular instability | ||
| + | **sympathetic nervous system | ||
| + | **drastic rise and fall of blood pressure | ||
| + | *localized (not generalized) tetanus also may occur | ||
| + | *increased muscle tones lasts more than 2 months | ||
| + | *muscle spasm emerges after increased muscle tones and lasts 1 month | ||
==diagnosis== | ==diagnosis== | ||
| + | *culture | ||
| + | **difficult and tricky | ||
| + | *PCR - toxin gene | ||
==treatment== | ==treatment== | ||
| + | |||
| + | ==prevention== | ||
| + | *wound debridement is crucial | ||
| + | **''C. tetani'' is anaerobe which grows in closed wound area | ||
2021年6月7日 (月) 17:14時点における版
| Navigation Menu | 
|
| 展開するGeneral issues of Vaccine |
|---|
| 展開するGeneral issues of Tropical med. |
|---|
| 展開するGeneral issues of Travel med. |
|---|
| 展開するImmunology |
|---|
| 展開するEpi & Stats |
|---|
| 展開するVirus |
|---|
| 展開するCOVID-19 |
|---|
| 展開するBacteria |
|---|
| 展開するRickettsia |
|---|
| 展開するProtozoa |
|---|
| 展開するFungi |
|---|
| 展開するNematode (roundworm) |
|---|
| 展開するTrematode (fluke, distoma) |
|---|
| 展開するCestode (tapeworm) |
|---|
| 展開するMedical Zoology |
|---|
pathogen
- Clostridium tetani
- gram positive terminal round shape (drumstick like) bacilli
- spore-forming
- drumstick looking is from spore
- means long term sustainability in soil
- strict anaerobe
- incubation 3-21 days (average 10 days)
- AB toxin
- blockade of releasing GABA in synapus
- convulsive contraction of voluntary muscles
- toxin binding is irreversible
epidmiology
clinical picture
- opisthotonus
- muscle spasm in opisthotonus is very painful
- trismus (lockjaw)
- difficulty opening mouth
- respiratory difficulties
- cardiovascular instability
- sympathetic nervous system
- drastic rise and fall of blood pressure
- localized (not generalized) tetanus also may occur
- increased muscle tones lasts more than 2 months
- muscle spasm emerges after increased muscle tones and lasts 1 month
diagnosis
- culture
- difficult and tricky
- PCR - toxin gene
treatment
prevention
- wound debridement is crucial
- C. tetani is anaerobe which grows in closed wound area
