「Yellow fever」の版間の差分
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| − | *WHO suggests case definitions to survey YF with suspected case as ''Any person with acute onset of fever, with jaundice appearing within 14 days of onset of the first symptoms''. | + | *WHO suggests case definitions to survey YF with '''suspected case''' as ''Any person with acute onset of fever, with jaundice appearing within 14 days of onset of the first symptoms''. |
{{quote|content= | {{quote|content= | ||
World Health Organization. (2022). Yellow Fever Outbreak Toolbox. https://www.who.int/emergencies/outbreak-toolkit/disease-outbreak-toolboxes/yellow-fever-outbreak-toolbox | World Health Organization. (2022). Yellow Fever Outbreak Toolbox. https://www.who.int/emergencies/outbreak-toolkit/disease-outbreak-toolboxes/yellow-fever-outbreak-toolbox | ||
| 11行目: | 11行目: | ||
| − | *A mathematical estimation using Bayesian model showed probability of asymptomatic infection, mild disease and severe disease as 55%, 33% and 12%, respectively, as well as case fatality rate among severe disease as 47%, but the 11 studies authors collected for the study were highly heterogeneous. | + | *A mathematical estimation using Bayesian model showed probability of asymptomatic '''infection''', '''mild disease''' and '''severe disease''' as '''55%''', '''33%''' and '''12%''', respectively, as well as '''case fatality rate among severe disease''' as '''47%''', but the 11 studies authors collected for the study were highly heterogeneous. |
{{quote | {{quote | ||
|content=Johansson, M. A., Vasconcelos, P. F. C., & Staples, J. E. (2014). The whole iceberg: Estimating the incidence of yellow fever virus infection from the number of severe cases. Transactions of the Royal Society of Tropical Medicine and Hygiene, 108(8), 482–487. https://doi.org/10.1093/trstmh/tru092 | |content=Johansson, M. A., Vasconcelos, P. F. C., & Staples, J. E. (2014). The whole iceberg: Estimating the incidence of yellow fever virus infection from the number of severe cases. Transactions of the Royal Society of Tropical Medicine and Hygiene, 108(8), 482–487. https://doi.org/10.1093/trstmh/tru092 | ||
| 17行目: | 17行目: | ||
| − | *A systematic review and meta-analysis concluded from 14 articles that case fatality rate of YF among severe disease is 39% (95%CI 31-47). | + | *A systematic review and meta-analysis concluded from 14 articles that '''case fatality rate of YF among severe disease''' is '''39%''' (95%CI 31-47). |
{{quote | {{quote | ||
|content=Servadio, J. L., Muñoz-Zanzi, C., & Convertino, M. (2021). Estimating case fatality risk of severe Yellow Fever cases: systematic literature review and meta-analysis. BMC Infectious Diseases, 21(1), 1–12. https://doi.org/10.1186/s12879-021-06535-4 | |content=Servadio, J. L., Muñoz-Zanzi, C., & Convertino, M. (2021). Estimating case fatality risk of severe Yellow Fever cases: systematic literature review and meta-analysis. BMC Infectious Diseases, 21(1), 1–12. https://doi.org/10.1186/s12879-021-06535-4 | ||
2023年9月7日 (木) 13:19時点における版
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Epidemiology
Due to non-specific acute febrile illness in its early stage including substantial number of asymptomatic cases, there are limitations to define the true incidence and case fatality rate of YF.
- WHO suggests case definitions to survey YF with suspected case as Any person with acute onset of fever, with jaundice appearing within 14 days of onset of the first symptoms.
|
World Health Organization. (2022). Yellow Fever Outbreak Toolbox. https://www.who.int/emergencies/outbreak-toolkit/disease-outbreak-toolboxes/yellow-fever-outbreak-toolbox |
- A mathematical estimation using Bayesian model showed probability of asymptomatic infection, mild disease and severe disease as 55%, 33% and 12%, respectively, as well as case fatality rate among severe disease as 47%, but the 11 studies authors collected for the study were highly heterogeneous.
|
Johansson, M. A., Vasconcelos, P. F. C., & Staples, J. E. (2014). The whole iceberg: Estimating the incidence of yellow fever virus infection from the number of severe cases. Transactions of the Royal Society of Tropical Medicine and Hygiene, 108(8), 482–487. https://doi.org/10.1093/trstmh/tru092 |
- A systematic review and meta-analysis concluded from 14 articles that case fatality rate of YF among severe disease is 39% (95%CI 31-47).
|
Servadio, J. L., Muñoz-Zanzi, C., & Convertino, M. (2021). Estimating case fatality risk of severe Yellow Fever cases: systematic literature review and meta-analysis. BMC Infectious Diseases, 21(1), 1–12. https://doi.org/10.1186/s12879-021-06535-4 |
transmission
- sylvatic cycle
- savannah cycle only in Africa
- urban cycle
- reason why YF doesn't exist in Asia is unknown
clinical features
- 3-6 days incubation
- infection phase
- remission phase
- most patients ended with remission phase
- intoxication phase
prevention
- new XRX-001 vaccine may be safer
