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*Diarrhea > 1 month, unexplained*'''Oral Candidiasis'''candidiasis
*Pulmonary TB, pluribacillary
*Severe bacterial LRIs, recurrent|-style="vertical-align:top"!SystemicNeurological
*Asymptomatic
*Acute HIV infection
*Lymphadenopathy, persistent
*Weight loss <10%, unexplained
*Weight loss >10%, unexplained
*Fever > 1 month, unexplained
*Sever bacterial infections (LRI, bone/joint infections, meningitis)
*Anemia < 8g/dL of Hb, unexplained
*Thrombocytopenia < 50<math>\times</math>10<math>^9</math>/L, unexplained
*HIV wasting syndrome
*TB, extrapulmonary
*Cytomegalovirus infection
*Non-typhoidal salmonellosis (NTS), recurrent*[[Coccidioidomycosis|coccidioidomycosis]] (America only)*[[Histoplasmosis|histoplasmosis]]*Atypical disseminated leishmaniasis*HIV-associated nephrophathy*HIV-associated cardiomyopathy|-!Malignancy||||*Kaposi's sarcoma*Lymphoma*Cervical carcinoma*HIV-associated solid tumors|} {|classstyle="wikitable"|vertical-!style="width:5%"|Stage!style="width:19%"|Skin!style="widthalign:19%top"|Oral & GI tract!style="width:19%"|Respiratory!style="width:19%"|Systemic!style="width:19%"|Malignancy|-!1|||
|-!2|*Herpes zoster*Papular pruritic eruptions*Seborrheic dermatitis*Fungal nail infections|*Angular cheilitis*Oral ulcer, recurrent|*URIs, recurrent|*Weight loss '''<10%, unexplained||-!3||*Diarrhea > 1 month, unexplained*'''Oral Candidiasis'''*Oral hairy leukoplakia (EBV-associated)*Acute necrotizing ulcerative stomatitis/gingivitis/periodontitis|*Pulmonary TB, pluribacillary*Bacterial LRIsunexplained
|
|-
!4
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*Herpes simplex infection (oral, genital) > 1 month
*[[Talaromycosis|Talaromycosis]] (Asia only)
|
*'''Esophageal Candidiasis'''
*Cryptosporidiasis, chronic
*Isosporiasis, chronic
|
*Pulmonary TB, paucibacillary
*Pneumocystis pneumonia (PcP)
*Severe bacterial LRIs, recurrent
*CNS toxoplamosis (Toxoplasmoma)
*HIV encephalopathy
*CNS cryptococcal infection (Cryptococcoma)
*Progressive multifocal leukoencephalopathy
編集の要約なし
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==疫学==
==WHO Clinical staging==
{{quote|content=[https://apps.who.int/iris/handle/10665/43699 WHO case definitions of HIV for surveillance and revised clinical staging and immunological classification of HIV-related disease in adults and children (2007)]}} {|class="wikitable" style="vertical-align:top"
|-
!style="width:4%"|Stage
!style="width:24%"|1<br>≈ CD4 500-!style="width:24%"|2<br>≈ CD4 350-500!style="width:24%"|3<br>≈ CD4 200-350!style="width:24%"|4<br>≈ CD4 -200|-style="vertical-align:top"
!Skin
|
*Herpes simplex infection (oral, genital) > 1 month
*[[Talaromycosis|Talaromycosis]] (Asia only)
|-style="vertical-align:top"
!Oral<br>GI tract
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*Oral ulcer, recurrent
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*Oral hairy leukoplakia (EBV-associated)
*Acute necrotizing ulcerative stomatitis/gingivitis/periodontitis
*Diarrhea > 1 month, unexplained
|
*'''Esophageal Candidiasis'''candidiasis
*Cryptosporidiasis, chronic
*Isosporiasis, chronic
|-style="vertical-align:top"
!Respiratory
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*URIs, recurrent
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*Bacterial LRIs
*Pulmonary TB, '''pluribacillary'''
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*Severe bacterial LRIs, recurrent*Pulmonary TB, '''paucibacillary'''
*Pneumocystis pneumonia (PcP)
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|
|
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*CNS toxoplamosis (Toxoplasmoma)
*HIV encephalopathy
*CNS cryptococcal infection (Cryptococcoma)
*Progressive multifocal leukoencephalopathy
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*Asymptomatic
*Lymphadenopathy, persistent
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*Weight loss '''>10%''', unexplained
*Fever > 1 month, unexplained
*Sever bacterial infections (LRI, bone/joint infections, meningitis)
*Anemia < 8g/dL of Hb, unexplained
*Thrombocytopenia < 50<math>\times</math>10<math>^9</math>/L, unexplained
|
*HIV wasting syndrome
*Extrapulmonary TB, extrapulmonary
*Cytomegalovirus infection
*Non-typhoidal salmonellosis (NTS), recurrent
*[[Coccidioidomycosis|coccidioidomycosisCoccidioidomycosis]] (America only)*[[Histoplasmosis|histoplasmosisHistoplasmosis]]
*Atypical disseminated leishmaniasis
*HIV-associated nephrophathy
*HIV-associated cardiomyopathy
|- style="vertical-align:top"
!Malignancy
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*Kaposi's sarcoma
*治療効果判定にはviral load
*CD4 countは初診時には有用だがフォローアップには無用；viral loadが大事
==Additional materials of HIV==
{{quote
|content=[https://www.nature.com/collections/mghkkdjlgx Nature Materials in HIV research]
https://www.nature.com/collections/mghkkdjlgx
}}
