「Viral hepatitis」の版間の差分

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==hepatitis virus==
 
==hepatitis virus==
 
*viral hepatitis is 4th major infectious disease worldwide
 
*viral hepatitis is 4th major infectious disease worldwide
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==hep B==
 
==hep B==
*
+
*family ''Hepadonavirus''
 +
*transmission route
 +
**vertical
 +
**horizontal
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***sexually transmitted
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***sharing needles
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===epidemiology===
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**240 mil. hep B carriers worldwide
 +
**0.5 mil. death per year
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*highly infectious; 10 virus copies are enough to infection
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===genotypes===
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*genotypes B and C prevalent in Asia
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*A in Europe
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===acute hep B===
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*genotype A is increasing in Japan
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**10% of genotype A carrier develope chronic carrier
 +
*6.3% of hep B carrier are co-infected by hep C
 +
===treatment===

2021年5月30日 (日) 16:49時点における最新版

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hepatitis virus

  • viral hepatitis is 4th major infectious disease worldwide
  • virus hepatitis is still increasing year by year
  • >250 mil. people living with viral hepatitis
  • hep B highly prevalent sub-Saharan children <5y/o
  • virus hepatitis has added to one of SDGs in 2016

hep A

  • food-borne, water-borne
  • infection route in Japan
    • mainly by raw oyster in HIV-negative
    • mainly MSM in HIV-positive

hep E

  • water-borne, contaminated meat-borne
    • incompletely cooked deer meat, pig intestine or liver
  • non-enveloped, positive-sense, single-stranded RNA virus
  • endemic in East to Southeast Asia
  • genotype 4 is strongly associated to fluminant hepatitis
  • hep E vaccine has already established in China

hep B

  • family Hepadonavirus
  • transmission route
    • vertical
    • horizontal
      • sexually transmitted
      • sharing needles

epidemiology

    • 240 mil. hep B carriers worldwide
    • 0.5 mil. death per year
  • highly infectious; 10 virus copies are enough to infection

genotypes

  • genotypes B and C prevalent in Asia
  • A in Europe

acute hep B

  • genotype A is increasing in Japan
    • 10% of genotype A carrier develope chronic carrier
  • 6.3% of hep B carrier are co-infected by hep C

treatment