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*rash to Stevens Johnson syndrome
*hepatic toxicity
*interact with rifampicinerifampicin
**never use in HIV-TB
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Dolutegravir<br>DTG
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*well tolerated
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*insomnia
*dizzyness
*paresthesia
*weight gain
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!Raltegravir<br>RAL
Lopinavir-Ritonavir<br>LPV-r
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*Twice daily
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*diarrhea
*metaboilc disturbance
**dyslipidemia
**impaired glucose tolerance
**lipodystrophy
*CYP3A4 interactions
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!Atazanavir<br>ATV-r
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*Once daily
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*hyperbilirubinemia, jaundice
*interact with rifampicin
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